Family

U4/U6 small nuclear ribonucleoprotein Prp31 (IPR027105)

Short name: Prp31

Family relationships

None.

Description

Prp31 is a component of the U4/U6-U5 snRNP complex that is involved in pre-mRNA splicing [PMID: 11867543]. It is required for U4/U6.U5 tri-snRNP formation [PMID: 10871341, PMID: 8604353]. Defects in PRPF31 are the cause of retinitis pigmentosa type 11 (RP11). RP leads to degeneration of retinal photoreceptor cells [PMID: 17412961, PMID: 8808602, PMID: 11545739].

GO terms

Biological Process

GO:0000398 mRNA splicing, via spliceosome
GO:0000244 spliceosomal tri-snRNP complex assembly

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0046540 U4/U6 x U5 tri-snRNP complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER