DNA helicase B (IPR027044)

Short name: Helb

Overlapping homologous superfamilies


Family relationships



DNA helicase B (EC: unwinds duplex DNA with 5'-3' polarity. It has single-strand DNA-dependent ATPase and DNA helicase activities and prefers ATP and dATP as substrates. It may facilitate cellular recovery from replication stress during S phase [PMID: 12181327, PMID: 7794903, PMID: 7596831].

GO terms

Biological Process

GO:0006269 DNA replication, synthesis of RNA primer
GO:0006261 DNA-dependent DNA replication

Molecular Function

GO:0004003 ATP-dependent DNA helicase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.