Proteasome subunit Rpn10 (IPR027040)

Short name: Proteasome_su_Rpn10

Overlapping homologous superfamilies

Family relationships


The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively [PMID: 22645313].

This family consists of the RC subunit Rpn10 (also known as subunit S5A or non-ATPase regulatory subunit 4). Rpn10 binds and presumably selects ubiquitin-conjugates for destruction [PMID: 8530351, PMID: 10809753].

GO terms

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0008540 proteasome regulatory particle, base subcomplex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.