Leucine-rich repeat-containing protein 4 (IPR026882)

Short name: Lrrc4

Overlapping homologous superfamilies

Family relationships



Leucine-rich repeat-containing protein 4 (Lrrc4), also known as netrin-G2 ligand 2 (NGL-2), is a synaptic adhesion protein. It regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. It organises the lamina/pathway-specific differentiation of dendrites. It plays a important role for auditory synaptic responses and is involved in the suppression of glioma [PMID: 15967442, PMID: 16980967, PMID: 17785411].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.