Vezatin (IPR026858)

Short name: Vezatin

Overlapping homologous superfamilies


Family relationships



Vezatin is a peroxisome transmembrane receptor that is involved in membrane-membrane and cell-cell adhesions. In the movement of peroxisomes, it binds to class V [PMID: 16678774] and class VIIa [PMID: 17379651] myosins to guide the organelle through the microtubules [PMID: 16678774] and allow pathogens to internalise themselves into host cells [PMID: 15090598]. In mouse cells, vezatin is crucial for spermatozoan production [PMID: 17379651]. It interacts with the cadherin-catenin complex bridging it to the C-terminal FERM domain of myosin VIIA [PMID: 11080149].

GO terms

Biological Process

GO:0098609 cell-cell adhesion

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.