Family

Vacuolar protein sorting-associated protein 13 (IPR026847)

Short name: VPS13

Family relationships

Description

Vacuolar protein sorting-associated protein 13 (VPS13) is involved in the delivery of proteins to the vacuole in vegetatively growing yeast [PMID: 9314526] and also regulates membrane morphogenesis during sporulation [PMID: 22442115]. In humans, the hereditary disorders chorea acanthocytosis and Cohen syndrome are caused by mutations in members of this family that are orthologues of yeast VPS13 (VPS13A and VPS13B respectively). The function of the different proteins in mammals has not been defined [PMID: 22442115, PMID: 15498460].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER