Adenomatous polyposis coli 2 (IPR026837)

Short name: APC2

Overlapping homologous superfamilies


Family relationships


Adenomatous polyposis coli protein 2 (APC2) promotes rapid degradation of CTNNB1 (beta-catenin) and may function as a tumor suppressor. It may function in Wnt signaling [PMID: 9823329, PMID: 10021369, PMID: 11691822].

GO terms

Biological Process

GO:0090090 negative regulation of canonical Wnt signaling pathway

Molecular Function

GO:0008013 beta-catenin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.