Domain

Adenomatous polyposis coli domain (IPR026831)

Short name: APC_dom

Domain relationships

None.

Description

The tumour suppressor protein adenomatous polyposis coli (APC) has a nuclear export activity as well as many different intracellular functions. The region close to the N terminus, termed APC-(129-250), consists of three alpha-helices forming two separate antiparallel coiled coils [PMID: 12070164]. This entry represents a domain towards the N terminus that covers part of this region.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam