NADH-quinone oxidoreductase subunit CD (IPR026662)
Short name: NDH-1_subunit_CD
Overlapping homologous superfamilies
- [NiFe]-hydrogenase, large subunit (IPR029014)
- NADH-quinone oxidoreductase, subunit D superfamily (IPR038290)
- NAD(P)H-quinone oxidoreductase subunit D/H (IPR022885)
- NADH-quinone oxidoreductase subunit CD (IPR026662)
NADH dehydrogenase I (NDH-1) shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centres, to quinones in the respiratory chain. It is composed of a number of different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
This entry represents the NuoC-NuoD fusion found in Aquificae, Bacteroidetes, Delta-and Epsilonproteobacteria. The NuoCD fusion protein found in the Alpha-, Beta- and Gammaproteobacteria is different enough that it seems to be another subfamily (see IPR023062). In many bacteria there are both the individual and fused versions.
- MF_01397 (NDH1_NuoCD_2)