Family

Centrosomal protein of 170kDa (IPR026644)

Short name: CEP170

Family relationships

None.

Description

Centrosomal protein of 170 kDa (Cep170) plays a role in microtubule organisation [PMID: 15616186].

Human Cep170 is constantly expressed throughout the cell cycle but phosphorylated during mitosis. Cep170 is a substrate of Polo-like kinase 1 (Plk1) [PMID: 15616186]. It is associated with the mature mother centriole. Upon DNA damage, it is phosphorylated probably by ATM or ATR [PMID: 19367708, PMID: 19144319, PMID: 19131326].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER