Opalin (IPR026609)

Short name: Opalin

Family relationships



Opalin (oligodendrocytic myelin paranodal and inner loop protein) is a brain specific, single-pass type I membrane protein [PMID: 9746342]. Its function is not clear. In mouse, it is expressed specifically in oligodendrocytes of the brain [PMID: 17442045, PMID: 18439243, PMID: 18490449]. It is induced by leukemia inhibitory factor (LIF) and cAMP analogs. It is suppressed in the presence of astrocytic or neural-stem-like differentiation factors such as bone morphotic protein (BMP) and fetal calf serum [PMID: 17442045].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.