Putative pyruvate, phosphate dikinase regulatory protein (IPR026565)

Short name: PPDK_reg

Overlapping homologous superfamilies


Family relationships


This is a family of proteins which are putative bifunctional serine/threonine kinase/phosphorylases involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalysing its phosphorylation/dephosphorylation [PMID: 16696949, PMID: 10683263].

In plants, the pyruvate, phosphate dikinase regulatory protein 1 (RP1) is a bifunctional serine/threonine kinase and phosphorylase involved in the dark/light-mediated regulation of PPDK by catalysing its phosphorylation/dephosphorylation. In the dark, RP1 phosphorylates the catalytic intermediate of PPDK (PPDK-HisP), inactivating it. Light exposure induces the phosphorolysis reaction that reactivates PPDK [PMID: 17996018, PMID: 6326674, PMID: 2834385, PMID: 10683263].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.