Secreted frizzled-related protein 2 (IPR026558)

Short name: SFRP2

Overlapping homologous superfamilies

Family relationships


Secreted frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts [PMID: 9096311]. They have a role in regulating cell growth and differentiation in specific cell types.

SFRP2 appears to have a role in development of the neural system, eyes, muscles and limbs [PMID: 10656762].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.