Pathways & interactions
KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein (IPR026555)
Short name: NSL3/Tex30
Overlapping homologous superfamilies
- Alpha/Beta hydrolase fold (IPR029058)
This entry includes the animal KAT8 regulatory NSL complex subunit 3 (KANSL3 or NSL3, also known as testis development protein PRTD), the testis-expressed sequence 30 proteins and their homologues, such as C. elegans SUMV-2 protein.
KAT8 regulatory NSL complex subunit 3 is part of the NSL complex that is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription [PMID: 20018852]. The function of the testis-expressed sequence 30 protein is not known.
SUMV-2 interacts with SUMV-1, and they may function together with MYS-2 in a nematode KAT8/MOF-like complex to antagonise the activity of the synMuv (synthetic multivulva) genes [PMID: 24882710].
This entry also includes uncharacterized bacterial proteins.
- PTHR13136 (PTHR13136)