Lymphocyte antigen 6 complex locus protein G6d/G6f (IPR026524)

Short name: LY6G6d/LY6G6f

Overlapping homologous superfamilies


Family relationships



This entry includes lymphocyte antigen 6 complex locus protein G6d and G6f, which are encoded in the MHC (major histocompatibility complex). Human and mouse G6d was found to be GPI-anchored cell surface proteins, highly expressed at the leading edges of cells, on filopodia, which are normally involved in cell adhesion and migration. The human G6f protein may play a role in the downstream signal transduction pathways involving GRB2 and GRB7, including the Ras-MAP kinase pathway [PMID: 12852788].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.