Family

Coiled-coil domain-containing protein 134 (IPR026321)

Short name: Coiled-coil_dom_con_pro_134

Family relationships

None.

Description

This coiled-coil domain-containing protein 134 (CCDC134) is a secretory protein that regulates the mitogen activated protein kinase (MAPK) pathway [PMID: 18087676]. Overexpression of CCDC134 inhibits transcriptional activity of Elk1 and phosphorylation of Erk and JNK/SAPK but not p38 MAPK [PMID: 18087676]. In humans, CCDC134 interacts with a transcription adaptor hADA2a [PMID: 22644376].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER