Family

Protein POF1B (IPR026186)

Short name: POF1B

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Proteins in this family may be involved in ovary development. Defects in POF1B are the cause of premature ovarian failure type 2B (POF2B), an ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterised by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol [PMID: 16773570].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER