Family

Interleukin-33 (IPR026145)

Short name: IL-33

Family relationships

None.

Description

This entry represents interleukin-33 (IL33), which that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8 [PMID: 17185418, PMID: 22215666]. It also serves as a warning signal between cells at times of injury or cell death [PMID: 22215666].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005125 cytokine activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER