Family

Retinoic acid-induced protein 2/sine oculis-binding protein homologue (IPR026092)

Short name: RAI2/SOBP

Family relationships

None.

Description

Retinoic acid (RA) has been shown to modulate the expression of a number of proteins implicated in the control of early embryonic development. One of these is retinoic acid-induced protein 2 (RAI2), which has been isolated in mouse [PMID: 8314004] and humans [PMID: 10049581].

Sine oculis-binding protein homologue (Jxc1, SOBP) is implicated in the development of the cochlea in the inner ear [PMID: 16962269]. Mutations in this gene also cause intellectual disability (ID) [PMID: 21035105].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER