Family

Fuzzy protein (IPR026069)

Short name: Fuzzy

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Drosophila Fuzzy protein plays a role in the organisation of cell polarity via a planar cell polarity (PCP) cascade. It is involved in the development of the hairs on the wings [PMID: 9374400].

Mouse Fuzzy protein is a probable planar cell polarity effector involved in cilium biogenesis. It may regulate protein and membrane transport to the cilium. It may also regulate the morphogenesis of hair follicles which depends on functional primary cilia [PMID: 19877275, PMID: 19767740, PMID: 20962855].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER