PPC89 centrosome localisation domain (IPR025925)

Short name: PPC89_CLD

Overlapping homologous superfamilies


Domain relationships



The N-terminal region of the fission yeast spindle pole body protein PPC89 has low similarity to the human Cep57 protein. The CLD or centrosome localisation domain of Cep57 and PPC89 is found towards the N terminus of the proteins. This region localises to the centrosome internally to gamma-tubulin, suggesting that it is either on both centrioles or on a centromatrix component. This N-terminal region can also multimerise with the N terminus of other Cep57 molecules. A microtubule-binding domain is found at the C terminus.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.