Repeat

Nuclear receptor repeat (IPR025900)

Short name: Nuclear_receptor_repeat

Description

This is a repeat involved in dimerisation of nuclear receptors proteins and in transcriptional regulation in general. It contains a Leu-Xaa-Xaa-Leu-Leu motif which has been characterised for the orphan nuclear receptor Dax-1, which represses the constitutively expressed protein Ad4BP/SF-1. The LXXLL motif plays in important role in binding of Dax-1 to Ad4BP/SF-1 [PMID: 12482977].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam