Domain

Polycomb-like MTF2 factor 2, C-terminal domain (IPR025894)

Short name: Mtf2_C_dom

Domain relationships

None.

Description

Mammalian Polycomb-like gene MTF2/PCL2 forms a complex with Polycomb repressive complex-2 (PRC2) and collaborates with PRC1 to achieve repression of Hox gene expression [PMID: 21059868]. The human MTF2 gene is expressed in three splicing variants, each of them contains the short C-terminal domain defined here.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam