Conserved Site

Friend of PRMT1 duplication (IPR025715)

Short name: FoP_duplication


This LDXXLDAYM region (where X is any amino acid) is duplicated in the C terminus of Friend of Prmt1 (Fop), which are chromatin-associated proteins that co-localise with facultative heterochromatin and are critical for oestrogen-dependent gene activation [PMID: 19858291]. The region also occurs in other proteins, including THO complex subunit 4 (O08583) and RNA and export factor-binding protein 2 (Q9JJW6).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.