YebF/Colicin-M immunity protein (IPR025603)

Short name: YebF/ColM_immunity

Overlapping homologous superfamilies

Family relationships


This family includes the colicin M immunity protein Cmi, and the protein of unknown function YebF. Cmi protects cells from the colicin M toxin, though the mechanism by which it achieves this is not known [PMID: 2820942]. The protein forms an alpha-beta fold and contains a disulphide bond that is essential for function [PMID: 21037007]. Although the function of YbeF is not known, it is secreted by E. coli, and contains the two conserved cysteine residues responsible for the disulphide bond in Cmi [PMID: 16369539].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.