Family

BCP1 family (IPR025602)

Short name: BCP1_family

Family relationships

None.

Description

This family of proteins includes BRCA2 and CDKN1A-interacting protein (BCCIP) and Bcp1. In fungi, Bcp1 is involved in nuclear export, actin cytoskeleton organisation and vesicular transport [PMID: 12912920]. Its homologue in human and mouse, BCCIP, may promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A/p21 and may be required for repair of DNA damage by homologous recombination in conjunction with BRCA2 [PMID: 14726710, PMID: 10878006, PMID: 15713648, PMID: 17947333].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PIRSF
PANTHER