Neprosin activation peptide (IPR025521)

Short name: Neprosin_propep

Overlapping homologous superfamilies


Domain relationships



Pitcher plants are insectivorous and secrete a digestive fluid into the pitcher. This fluid contains a mixture of enzymes including peptidases. One of these is neprosin, characterized from the pitcher plant Nepenthes ventrata. This peptidase is of unknown catalytic type and is unaffected by standard peptidase inhibitors. Unusually, activity is directed towards prolyl bonds, but unlike most peptidase that cleave after proline, there is no restriction on sequence length or position of the proline residue. The peptidase is secreted and is presumed to possess an N-terminal activation peptide [PMID: 27481162]. This domain corresponds to the presumed activation peptide.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.