Anaphase-promoting complex subunit 1 (IPR024990)

Short name: Apc1

Family relationships



Apc1 is the largest of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes [PMID: 11179667, PMID: 16896351]. Infection of human fibroblasts with human cytomegalovirus (HCMV) leads to cell cycle dysregulation, which is associated with the inactivation of the anaphase-promoting complex [PMID: 17942546].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005680 anaphase-promoting complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.