E3 ubiquitin-protein ligase, SMURF1 type (IPR024928)

Short name: E3_ub_ligase_SMURF1

Overlapping homologous superfamilies


Family relationships



This entry represents a set of E3 ubiquitin-protein ligases which accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates, like SMURF1 [PMID: 11956316], Pub1 [PMID: 10458166] and RSP5 [PMID: 9858558]. All of them contain a HECT domain [PMID: 10998601].

GO terms

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

Molecular Function

GO:0061630 ubiquitin protein ligase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.