Domain

Enoyl reductase FAD binding domain (IPR024906)

Short name: Eno_Rdtase_FAD-bd_dom

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents the C-terminal domain of trans-2-enoyl-CoA reductase that binds to FAD. The activity was characterised in Euglena where an unusual fatty acid synthesis path-way in mitochondria performs a malonyl-CoA independent synthesis of fatty acids leading to accumulation of wax esters, which serve as the sink for electrons stemming from glycolytic ATP synthesis and pyruvate oxidation [PMID: 15569691]. The full enzyme catalyses the reduction of enoyl-CoA to acyl-CoA.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam