Family

Coilin (IPR024822)

Short name: Coilin

Family relationships

None.

Description

Coilin is a nuclear phosphoprotein that concentrates within Cajal bodies (CBs) and has a role in small nuclear ribonucleoprotein (snRNP) biogenesis [PMID: 15862129]. Coilin also acts to repress polymerase I activity in response to cisplatin-induced DNA damage, which could indicate a link between the DNA damage response and the inhibition of rRNA synthesis [PMID: 21289084].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER