Anaphase-promoting complex subunit 4 (IPR024789)

Short name: APC4

Family relationships


The anaphase-promoting complex (APC) or cyclosome is a multi-subunit E3 protein ubiquitin ligase that regulates important events in mitosis, such as the initiation of anaphase and exit from telophase. The APC, in conjunction with other enzymes, assembles multi-ubiquitin chains on a variety of regulatory proteins, thereby targeting them for proteolysis by the 26S proteasome.

This family represents the anaphase-promoting complex subunit 4 (APC4). This entry also includes APC4 homologue, EMB-30, from Caenorhabditis elegans [PMID: 10749938].

GO terms

Biological Process

GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0030071 regulation of mitotic metaphase/anaphase transition

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005680 anaphase-promoting complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.