Domain

B-cell lymphoma 9, beta-catenin binding domain (IPR024670)

Short name: BCL9_beta-catenin-bd_dom

Domain relationships

None.

Description

The Wnt pathway plays a role in embryonic development, stem cell growth and tumorigenesis. B-cell lymphoma 9 (BCL9) associates with beta-catenin and Tcf in the nucleus when the Wnt pathway is stimulated leading to the transactivation of Wnt target genes [PMID: 17052462].

This entry represents a beta-catenin binding domain found in BCL9 and BCL9 homologues.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam