Domain

Tbk1/Ikki binding domain (IPR024581)

Short name: TBD

Domain relationships

None.

Description

The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain able to bind kinases which is essential for poly(I:C)-induced IRF activation [PMID: 17568778]. The domain is found in the SINTBAD, TANK and NAP1 proteins. This domain is predicted to form an alpha-helix with residues essential for kinase binding clustering on one side [PMID: 17568778].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam