Family

Bcl-2-interacting killer (IPR024579)

Short name: Bcl2-int_killer

Family relationships

None.

Description

Bcl-2-interacting killer promotes cell death in a manner similar to the death-promoting members of the Bcl-2 family, Bax and Bak. Its death-promoting activity can be suppressed by coexpression of Bcl-2, Bcl-XL, EBV-BHRF1 and E1B-19 kDa proteins, suggesting that it may be a common target for both cellular and viral anti-apoptotic proteins [PMID: 7478623].

GO terms

Biological Process

GO:0006915 apoptotic process

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
ProDom
Pfam