Domain

Ribonuclease HIII, N-terminal (IPR024568)

Short name: RNase_HIII_N

Domain relationships

None.

Description

Ribonuclease HIII EC:3.1.26 cleaves RNA from DNA-RNA hybrids. It catalyses endonucleolytic cleavage to 5'-phospho-monoesters. Two types of ribonuclease H in Bacillus subtilis, RNase HII (rnhB) and RNase HIII (rnhC), are both known experimentally and are quite similar to each other. The only RNase H homologue in the Mycoplasmas resembles rnhC. Archaeal forms resemble HII more closely than HIII [PMID: 9888800].

This entry represents the uncharacterised N-terminal domain of bacterial RNase HIII.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
Pfam