Family

Coiled-coil domain-containing protein 90-like (IPR024461)

Short name: DUF1640

Family relationships

Description

This entry includes coiled-coil domain-containing proteins 90 (CCDC90) and related proteins. CCDC90A was reported to be a regulator of the mitochondrial calcium uniporter (MCU) and hence was renamed MCUR1. However, studies in mammals and in yeast homologue fmp32 have shown that it is a cytochrome c oxidase assembly factor and does not directly regulate MCU [PMID: 25565209]. The role of CCDC90B proteins is still not known.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER