Domain

Initiator binding protein 39kDa, C-terminal (IPR024238)

Short name: IBP39_C

Overlapping homologous superfamilies

Domain relationships

None.

Description

Initiator binding protein 39kDa (IBP39) recognises the initiator (Inr), which in Trichomonas vaginalis is solely responsible for transcription start site selection. IBP39 consists of an N-terminal Inr binding domain, a flexible linker, and a C-terminal domain. The C-terminal domain interacts with the RNAP II large subunit C-terminal domain. Binding of IBP39 to Inr recruits RNAP II and initiates transcription [PMID: 14622596].

This entry represents the C-terminal domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam