Bin3-type S-adenosyl-L-methionine binding domain (IPR024160)

Short name: BIN3_SAM-bd_dom

Overlapping homologous superfamilies

Domain relationships



Bin3 contains a tripartite S-adenosyl-L-methionine (SAM) binding motif with three sequence motifs, I/Ia, II, and III [PMID: 10717484]. It is found in the following proteins:

  • Drosophila melanogaster probable methyltransferase Bin3 (EC 2.1.1.-). It interacts with bicoid/bcd.
  • Human 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) or Bicoid-interacting protein 3 homologue (Bin3 homolog), a S-adenosyl-L- methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilise it.
  • Caenorhabditis elegans probable methyltransferase Y17G7B.18 (EC 2.1.1.-).

This entry represents the Bin3-type SAM binding domain.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008168 methyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles