Family

Phosphoglucosamine mutase, archaeal type (IPR024086)

Short name: GlmM_arc-type

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

The entry represents a group of phosphoglucosamine mutases (encoded by gene GlmM) from archea and bacteria. MMP1680 protein from Methanococcus maripaludis in this family has been characterised as the archaeal protein responsible for the second step of UDP-GlcNAc biosynthesis [PMID: 18263721]. MMP1680 protein catalyses the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. This entry also includes a number of sequences from non-archaea in the Bacteroides, Chlorobi, Chloroflexi, Planctomycetes and Spirochaetes lineages [PMID: 18263721, PMID: 16930487].

In some organisms including Leptospira, this archaeal GlmM is found adjacent to the GlmS as well as a putative GlmU non-orthologous homologue [PMID: 16930487].

This family of phosphoglucosamine mutases and the bacterial family of phosphoglucosamine mutases represented by IPR006352 are members of the larger phosphoglucomutase/phosphomannomutase family (characterised by three domains: IPR005844 , IPR005845 and IPR005846 ), but are not nearest neighbours to each other.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008966 phosphoglucosamine mutase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs
CDD