Homologous Superfamily

Neurolysin/Thimet oligopeptidase, N-terminal (IPR024080)

Short name: Neurolysin/TOP_N

Description

Thimet oligopeptidase and neurolysin are closely related zinc-dependent metallopeptidases that metabolize small bioactive peptides. They cleave many substrates at the same sites, but they recognise different positions on others [PMID: 17251185].

This entry represents the up-down alpha bundle domain found at the N terminus of these and related M3 peptidases.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
GENE3D