Inosose dehydratase (IPR023952)

Short name: IolE

Overlapping homologous superfamilies

Family relationships


This enzyme catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol) [PMID: 14993306]. It uses glutathione and cobalt or manganese as cofactors and belongs to the iolE/mocC family.

GO terms

Biological Process

GO:0019310 inositol catabolic process

Molecular Function

GO:0030145 manganese ion binding
GO:0050114 myo-inosose-2 dehydratase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.