Bis(5'-nucleosyl)-tetraphosphatase PrpE (IPR023937)

Short name: Bis(5'-nucleosyl)-tetraP_PrpE

Overlapping homologous superfamilies

Family relationships



Bis(5'-nucleosyl)-tetraphosphatase (PrpE) asymmetrically hydrolyses Ap4p to yield AMP and ATP, but does not hydrolyse Ap2a or Ap6A. It also has an ATPase activity. In Bacillus subtilis, it has been shown to dephosphorylate phosphotyrosine but not phosphoserine or phosphothreonine from phosphorylated peptides [PMID: 12059787].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
GO:0016151 nickel cation binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.