Amino acid/peptide transporter family, dipeptide permease D (IPR023777)

Short name: AA/pep_transptr_DtpD

Overlapping homologous superfamilies


Family relationships


The transport of peptides into cells is a well-documented biological phenomenon which is accomplished by specific, energy-dependent transporters found in a number of organisms as diverse as bacteria and humans. The amino acid/peptide transporter family of proteins is distinct from the ABC-type peptide transporters and was uncovered by sequence analysis of a number of recently discovered peptide transport proteins [PMID: 7476181]. This family consists of bacterial proton-dependent oligopeptide transporters, although they are found in yeast, plants and animals. They function by proton symport in a 1:1 stoichiometry, which is variable in different species. All of them are predicted to contain 12 transmembrane domains, for which limited experimental evidence exists.

This entry represents a family of probable proton-dependent permeases that transport dipeptides.

GO terms

Biological Process

GO:0042938 dipeptide transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005887 integral component of plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.