Homologous Superfamily

RbsD-like superfamily (IPR023750)

Short name: RbsD-like_sf

Overlapping entries


RbsD is a component of the ribose operon. It was originally thought to be a high affinity ribose transport protein, but further analysis [PMID: 16731978] shows that it is a D-ribose pyranase EC:5.5.1.n1. It catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. It also catalyzes the conversion between beta-allofuranose and beta-allopyranose.

FucU is a component of the fucose operon and is a L-fucose mutarotase EC:5.1.3.n2, involved in the anomeric conversion of L-fucose. It also exhibits a pyranase activity for D-ribose [PMID: 16731978].

Both have been classified in the RbsD/FucU family of proteins. Members of this family are ubiquitous having been found in organisms from eubacteria to mammals.

The crystal structure of Bacillus subtilis RbsD reveals a 3 layers (alpha-beta-alpha) subunit that associates into a homodecameric assembly [PMID: 12738765].

GO terms

Biological Process

GO:0005996 monosaccharide metabolic process

Molecular Function

GO:0016853 isomerase activity
GO:0048029 monosaccharide binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.