2,3-diketo-L-gulonate reductase (IPR023689)
Short name: Diketo_gul_Rdtase
Overlapping homologous superfamilies
- Malate/L-lactate dehydrogenase-like (IPR003767)
- 2,3-diketo-L-gulonate reductase (IPR023689)
This entry represents a family of bacterial 2,3-diketo-L-gulonate reductases, which catalyse the reduction of 2,3-diketo-L-gulonate in the presence of NADH [PMID: 11741871]. The gene operon yiaK-S (of which yiaK encodes for the 2,3-diketo-L-gulonate reductase) is believed to encode proteins which are involved in the utilisation of rare sugars for growth. This enzyme relies on NAD-tartrate binding to produce a more open active site; the conformation of the free enzyme is incompatible with substrate binding [PMID: 14718529].
GO:0055114 oxidation-reduction process
No terms assigned in this category.
- MF_00820 (Diketo_gul_reduc)