Zinc transporter ZitB (IPR023500)

Short name: Zn_transptr_ZitB

Overlapping homologous superfamilies

Family relationships


This entry is represented by ZitB, which is involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc, whereas ZntA is required for growth at more toxic concentrations [PMID: 11443104, PMID: 22459916]. ZitB is potentially capable of transporting not only zinc but also cadmium, nickel and copper [PMID: 14715669, PMID: 19039702].

GO terms

Biological Process

GO:0006829 zinc ion transport

Molecular Function

GO:0005385 zinc ion transmembrane transporter activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.