ADP-ribosylation factor-like 2-binding protein, domain (IPR023379)

Short name: ARF-like_2-bdp_dom

Overlapping homologous superfamilies

Domain relationships



This domain is found in ADP-ribosylation factor-like 2 (ARF2) binding protein, also known as BART, and in uncharacterised proteins.

BART binds specifically to ARF2.GTP with a high affinity. However, it does not bind to ARF2.GDP. It is thought that this specific interaction is due to BART being the first identified ARF2-specific effector. The function is not completely characterised [PMID: 10488091]. BART is predominantly cytosolic but can also be found to be associated with mitochondria. BART is also involved in binding to the adenine nucleotide transporter ANT1 [PMID: 11809823].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.