Homologous Superfamily

Acetoacetate decarboxylase domain superfamily (IPR023375)

Short name: ADC_dom_sf


Acetoacetate decarboxylase (ADC) is involved in solventogenesis in certain bacteria, which occurs at the end of the exponential growth phase when there is a metabolic switch from classical sugar fermentation with the production of acetate and butyrate to the re-internalisation and oxidation of these acids to acetate and butanol [PMID: 11824611]. In Clostridium, SpoOA controls the switch from acid to solvent production. A SpoAO-binding motif occurs in the gene encoding ADC [PMID: 10972834].

This superfamily represents the beta barrel structural domain found in acetoacetate decarboxylases.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.