Homologous Superfamily

Outer surface lipoprotein domain superfamily (IPR023322)

Short name: OM_lipoprot_dom_sf

Overlapping entries


The ospA and ospB genes encode the major outer membrane proteins of the Lyme disease spirochaete Borrelia burgdorferi [PMID: 2761388]. The deduced gene products OspA and OspB, contain 273 and 296 residues respectively [PMID: 2761388]. The two Osp proteins show a high degree of sequence similarity, indicating a recent evolutionary event. Molecular analysis and sequence comparison of OspA and OspB with other proteins has revealed similarity to the signal peptides of prokaryotic lipoproteins [PMID: 2761388, PMID: 1560779].

This superfamily represents a structural domain, which consists of 21 stranded sheet partly folded upon itself at the ends, found in outer surface lipoproteins.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.